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Keyhole surgery for gallstones
The anatomy of the biliary tree.
The biliary tree transmits and stores bile, made in the liver,
to the small intestine where it is used to help to digest fats.
Bile is made in the liver and contains bile salts, bile acids, bile
pigments and cholesterol. Bile is secreted into the biliary tree
and stored in the gallbladder. After eating, bile is discharged
into the small intestine, where it helps to digest fats.

Why do gallstones form?
Gallstones
form in the gallbladder when the balance between the cholesterol
content of the bile and the bile salt content of bile, leads to
cholesterol crystal formation and the subsequent development of
gallstones. The conditions for producing stone forming bile are
increased in women in the Western world, typically related to pregnancy
or contraceptive pill, overweight, severe weight loss and where
there is a family predisposition. Gallstones can also occur in men
and in children.
Gallstone symptoms.
Typically symptoms arising from gallstones are of moderate or severe
pain in the right upper part of the abdomen. This pain can radiate
around to the back and shoulder blades and may also be experienced
in the lower chest. Occasionally this pain is mistaken for a heart
attack. When the pain is present the patient may feel nauseated
and vomit. If the pain persists for greater than 12 hours, it is
likely that the patient has an infective complication of gallstones
called cholecystitis. Some patients experience no symptoms from
their gallstones.
What are the complications
of gallstones?
Gallstones frequently cause abdominal pain and loss of appetite.
Cholecystitis If infection develops
in the gallbladder (cholecystitis) the patient may experience continuous
pain, worse on movement, a fever, generalised malaise and nausea.
Jaundice If gallstones pass from the
gallbladder into the bile duct they can lead to obstruction of the
flow of bile, leading to jaundice, where the eyes and skin become
discoloured yellow, the urine becomes dark orange and the stools
become putty coloured.
Pancreatitis If the drainage pancreas
gland is blocked the patient may experience pancreatitis which is
inflammation of the pancrease gland. This causes severe abdominal
pain and generalised illness.
Mucocoel If the gallstone obstructs
the neck of the gallbladder, mucous may accumulate within the gallbladder,
causing it to swell up in a so-called mucocele. This can present
with a mass and is also more likely to become infected, leading
to cholecystitis.
Empyema A pus filled gallbladder is
termed an empyema and is more common in older patients, particularly
diabetics.
Perforation of the gallbladder. Occasionally
with severe infections, particularly in older patients, the gallbladder
may perforate, leading to generalised biliary peritonitis.
Small bowel obstruction Gallstones
occasionally pass through an abnormal communication to the small
bowel (fistula) leading to obstruction of the small intestine (gallstone
ileus). This gives rise to pain, abdominal distension and vomiting.
Gallbladder cancer Cancer of the gallbladder
is associated with the presence of gallstones in most cases, but
its incidence is extremely rare.
How is the diagnosis of
gallstones made?
History Diagnosis is made by taking
a careful history of the symptoms, followed by physical examination
of the abdomen.
Ultrasound The most reliable form of
diagnostic test for gallstones is the ultrasound scan. Ultrasound
uses harmless high frequency sound waves to show up gallstones and
a thick walled gallbladder. If there are stones in the bile duct
they may show up on an ultrasound and may also lead to increase
in the width of the bile duct which can be measured by ultrasound.
Futher information on ultrasound can be found here
Magnetic resonance imaging Stones in
the bile duct can be diagnosed by ultrasound scanning or magnetic
resonance imaging (MRI). MRI uses strong magnetic fields to cause
vibration which can be detected by a scanner. Futher information
on MRI can be found here
ERCP ( Endoscopic Reterograde Cholangio-pancreatography)
is an endoscopic technique through the mouth (ERCP). ERCP can also
be used to diagnose and remove gallstones within the bile duct.
Futher information on ERCP can be found here

ERCP showing a large stone in the common
bile duct. The patient was jaundiced and stents were inserted to
decompress the obstruction.
Treatment of gallstones.
Most patients with symptomatic gallstones opt for treatment in
order to get rid or their symptoms and to prevent complications
in the future. Patients with mild symptoms may benefit from lifestyle
modification, such as a low-fat diet. However, many patients will
be keen to avoid recurrent attacks of the severe pain that they
have experienced in the past and to avoid complications in the future.
For patients fit for a general anaesthetic, keyhole surgery to remove
the gallbladder (laparoscopic cholecystectomy) is the gold standard
treatment. This can be performed with a single overnight stay or
as a day case in the majority of cases. Alternative treatments such
as attempts to dissolve the gallstones and attempts to shatter them
with ultrasound waves are generally felt to be too ineffective and
to have too high a complication rate to be widely applicable.
About keyhole surgery for
gallstones.
Laparoscopic cholecystectomy (keyhole surgery for gallstones) is
one of the most widely performed abdominal operations. Surgeons
with a special interest in keyhole surgery will perform in excess
of 100 procedures each year. They will also be able to undertake
more advanced techniques, such as x-raying the bile duct during
the operation and exploring the bile duct by keyhole surgery in
order to remove gallstones from the bile duct. Specialist keyhole
surgeons achieve very low rates of conversion to open operation
and avoid complications of surgery such as damage to the common
bile duct. Bile duct injury is a serious complication, which may
require major reconstructive surgery. Patients who experience an
uncomplicated operation often go home the day following surgery
or can occasionally be treated as a day case if their general condition
and home circumstances are favourable.
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